PK Support Our Cause Comprehensive assessment of the distribution, half-life, and bioavailability of your compounds often requires supplemental assays and experiments. IAS fosters your overall understanding of the pharmacokinetic properties of a compound or development program by providing a full complement of PK screening assays. These services are intended to reduce your workload and aide in the prioritization of compounds for further screening. To this end, IAS routinely performs fully integrated PK studies (in vivo + bioanalysis+PK parameter estimation), plasma protein binding assays, plasma stability assays, solubility assays, discovery formulation services and Caco-2 permeability assays.

Experience and Expertise IAS scientists bring experience from industry positions in pharmaceutical sciences, analytical chemistry, pharmacokinetics and toxicology. This cross-functional experience of IAS team members is the key ingredient to developing answers to critical PK-related questions. IAS leverages the power of its LC/MS platforms and the experience of its analysts to offer assays that enable intelligent compound selection.